Methods Overview

AP - Antioxidative Power
ABBREVIATION:
AP
DESCRIPTION:
Measures the antioxidative capacity and reactivity of raw materials and final products. Standardized to ascorbic acid (vit. C). Enables choice of actives, control of the long term stability, optimization of proceeding/ storing
APPLICABLE FOR:
  • raw materials
  • food
  • cosmetic formulations
CATEGORY:
In vitro
CHARACTERIZATION:
  • Antioxidative activity of products
  • Activity compared to vitamin C or vitamin E
SAP - Skin Antioxidative Power
ABBREVIATION:
SAP
DESCRIPTION:
Measures the antioxidative activity of the skin. Measures the activity of topically applied antioxidants
APPLICABLE FOR:
  • cosmetic formulations
  • raw materials
CATEGORY:
Ex vivo - Skin biopsy
CHARACTERIZATION:
  • Penetration ability of antioxidants.
  • Enhancement of the antioxidative activity of skin
SAR - Skin Antioxidative Retention
ABBREVIATION:
SAR
DESCRIPTION:
Measures the antioxidative activity of the skin after free radical damage (UV-radiation). Measures the protective effect of topically applied antioxidants/ free radical scavengers
APPLICABLE FOR:
  • cosmetic formulations
  • raw materials
CATEGORY:
Ex vivo - Skin biopsy
CHARACTERIZATION:
  • Penetration ability of antioxidants
  • Enhancement of the antioxidative activity of skin
RSF - Radical Skin Protection Factor
ABBREVIATION:
RSF
DESCRIPTION:
Measures the free radical amount inside skin during UV-radiation. Measures the protective effect of sunscreens, UV-filters, and radical scavengers
APPLICABLE FOR:
  • cosmetic formulations
CATEGORY:
Ex vivo - Skin biopsy
CHARACTERIZATION:
  • Avoidance of the formation of x % free radicals in the skin
  • Protection from free radical damage
RP - Radical Potential
ABBREVIATION:
RP
DESCRIPTION:
Measures the amount of free radicals inducible inside a sample by UV-radiation. Characterizes the oxidation state related to rancidity.
APPLICABLE FOR:
  • raw materials
  • food
  • cosmetic formulations
CATEGORY:
In vitro
CHARACTERIZATION:
  • Amount of inducible free radicals
  • Oxidative state of the sample
RHF - Radical Hair Protection Factor
ABBREVIATION:
RHF
DESCRIPTION:
Measures the free radical amount inside the hair during UV-radiation. Measures the protective effect of sunscreens, UV-filters, antioxidants, and other radical scavengers
APPLICABLE FOR:
  • cosmetic formulations
  • raw materials
CATEGORY:
Ex vivo - Hair
CHARACTERIZATION:
  • Avoidance of the formation of x % free radicals in the hair
  • Protection from free radical damage
CSS - Carrier System Stability
ABBREVIATION:
CSS
DESCRIPTION:
Evaluates the stability of carrier systems inside a cosmetic formulation (cream, lotion)
APPLICABLE FOR:
  • liposomes
  • nanosomes
  • nanoparticles
CATEGORY:
In vitro
CHARACTERIZATION:
  • Stability and physical integrity of x % liposomes in a cosmetic formulation
HI - Structural Hair Integrity
ABBREVIATION:
HI
DESCRIPTION:
Detection of damaged hair, determination of protective effects of hair care formulations and actives
APPLICABLE FOR:
  • cosmetic formulations
  • raw materials
CATEGORY:
Ex vivo - Hair
CHARACTERIZATION:
  • Investigation of protection strategies against hair damage
Anti-Pollution
ABBREVIATION:
Anti-Pollution
DESCRIPTION:
Detection of free radicals and lipid peroxidation in the skin under model pollutant conditions
APPLICABLE FOR:
  • cosmetic formulations
  • raw materials
CATEGORY:
Ex vivo – Skin biopsy
CHARACTERIZATION:
  • Avoidance of the formation of x% free radicals in the skin
  • Protection from pollution-induced free radical damage